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HyaloFix reverse filler HyaloFix reverse filler uses hyaluronidase enzyme to reverse filler.
Each patient must remember that Hyaluronidase enzyme is used ‘off-licence’. This means that there have not been studies done to test its use with fillers. These studies recommend its use for filler reversal. HyaloFix Reverse filler with hyaluronic acid gel (HA) is effective.
There is a good paper in ‘Journal of Drugs and Dermatology’  called ‘Reversing Facial Fillers – Interactions between Hyaluronidase and commercially available Hyaluronic Acid (HA) based fillers’ by Rao V Chi S and Woodward J.
They point out that the available Hyaluronidase and HA fillers have physical properties. Properties that influence their action in a time and dose-dependent manner. We all interact with fillers in different ways. Thus, Different people may interact with a different Hyaluronidase. To achieve the desired cosmesis when aiming to adjust delicate facial fillers, we must choose the right one.
The paper confirms that Restylane was the easiest to dissipate using the enzyme. They tested a hyaluronidase enzyme called Vitrase. Juvederm was the next easiest, with Belotero being the most difficult to reverse with HyaloFIx reverse filler, still retaining its form.
New HA fillers are introduced onto the market with slightly different structures and components. This will again influence the interaction between available Hyaluronidase and fillers. We will all learn more about Hyaluronidase and its effect on the multitudinous Hyaluronic fillers.

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